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FIG. 01 // ACTIVE_STUDY_ODYSSEY

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CHEM 201 // ACTIVE_STUDY_ODYSSEY
STAGE 01 • STUDY BITE 1
01

S_N2 SUBSTITUTION MECHANISM

One-step backside nucleophilic attack. Causes 100% Walden stereochemical inversion. Bulky alkyl groups block backside attack due to steric hindrance.

Active Study OdysseyCHEM 201
STAGE 01 • CHECKPOINT 01
02

Does an S_N2 mechanism lead to retention or inversion of configuration?

Answer:
Active Study OdysseyCHEM 201
STAGE 01 • STUDY BITE 2
03

MARKOVNIKOV’S ADDITION RULE

In HX addition across an asymmetric alkene, H attaches to the carbon with more hydrogens, creating the most thermodynamically stable carbocation intermediate.

Active Study OdysseyCHEM 201
STAGE 01 • CHECKPOINT 02
04

True or False: Hydrogen attaches to the carbon with fewer hydrogen atoms.

True
False
Active Study OdysseyCHEM 201
STAGE 02 • STUDY BITE 1
05

HÜCKEL’S (4n + 2) π RULE

A cyclic, planar, fully conjugated ring is exceptionally stable (aromatic) only if it contains (4n + 2) π electrons. Benzene qualifies with n = 1 (6 π electrons).

Active Study OdysseyCHEM 201
STAGE 02 • CHECKPOINT 01
06

How many π electrons does Benzene have to qualify as aromatic?

4 π electrons
6 π electrons
8 π electrons
Active Study OdysseyCHEM 201
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FIG. 02 // COHORT_DISCOVERY

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